Corrected QT Dispersion within the First 72 Hours of Acute ST Elevation Myocardial Infarction in Salahaddin General Hospital-Tikrit-Iraq Sultan Hasan Ismail* F.I.C.M.S - Department of Medicine, College of Medicine, University of Tikrit, Tikrit, Iraq *Corresponding author: Hasan Ismail Sultan, Assistant Professor, Department of Medicine, College of Medicine, Tikrit University. Email: Aymen.altae@tu.edu.iq Phone. 009647719330585
Online published on 27 November, 2019. Abstract Background Increase QT dispersion following acute myocardial infarction has been linked to increased heterogeneity of ventricular repolarization, which associated with an adverse prognosis in a diversity of patients. Objective Is to evaluate the effect of QTc dispersion in patients with acute ST elevation myocardial infarction (STEMI) at admission and at 72 hours. Patients and Method A cross sectional study included 60 patients with acute STEMI admitted to coronary care unit in Salahaddin General Hospital during the period from January to Jun 2019. Corrected QT (QTc) dispersion was measured in all patients, which defined as the difference between the maximum QTc interval and minimum QTc interval for a given heart rate. Results A 60 patients with acute STEMI were enrolled in this study, 41 (68.3%) of patients were males. The mean age of males’ patients was 54.66±12.13 years while the mean age of females’ patients was 62.84±13.00 years, with significant earlier age affection of males’ patients. There were significant reduction in the QTc dispersion at admission from QTc dispersion at 72 hours in those presented with anterior and inferior acute myocardial infarction than lateral and posterior acute myocardial infarction. Moreover, malignant ventricular arrhythmias (VT and VF) were present in 8 (13.3%) patients. QTc dispersion at admission was higher in ventricular tachyarrhythmias group (97.07±27.27 msec) than non-arrhythmias group (59.18±26.98 msec). QTc dispersion was higher in heart failure group, with significant difference between QTc dispersion at admission and QTc dispersion at 72 hour in this group, with P value < 0.001. Conclusion QTc dispersion is higher at the time of admission of patients with acute STEMI. QTc dispersion is higher in patients with anterior wall acute STEMI. Increase QTc dispersion can predict development of ventricular tachyarrhythmias and heart failure in patients with acute STEMI. Top Keywords QT dispersion, STEMI, Tikrit University, ventricular arrhythmias. Top |