Antimicrobial Resistance of Neisseria Gonorrheae in Female Patients Attending Special Gynaecological Care Clinics in Dour District Farhan Rafal K.* Department of Microbiology, College of Medicine, Tikrit University, Salahdine, Iraq *Corresponding Author: Rafal K. Farhan M.B.C.H.B, M.S.C, P.H.D, Department of Microbiology, College of Medicine, Tikrit University, Salahdine, Iraq. Email: Aymen. Altae@tu.edu.iq. Phone: 009647719330585
Online published on 27 November, 2019. Abstract Neisseria gonorrheae, a strict human pathogen, is the agent of the disease gonorrhea, a sexually transmitted infection which if left untreated it will cause complications like pelvic inflammatory disease and infertility. Antimicrobial resistance has emerged for all the regularly used therapeutic agents throughout decades. The aim of this study is to find the most successful antimicrobial, even herbal, to treat this second most common genital infection worldwide. This study was achieved from March 2018 to June 2018 on 80 female patients attending gynaecological clinics in Dour district of which 24 cases were proved as gonococcal infection by various microbiological tests like Gram's stain, culture on non selective chocolate agar, selective Modified Thayer Martin (MTM) agar, oxidase positive results, and genetic proof through orf1gene. The antibiotic sensitivity tests revealed 15(62.5%) resistance to Amoxiclav, 19(79.1%) resistance to Ciprofloxacin, 5(20.8%) resistance to Ceftriaxone, 20(83.3%) resistant to Azithromycin, and 22(91.6%) resistant to Doxycycline by disc diffusion method. MIC results were 64 μg/ml for Azithromycin, 16 μg/ml for Ceftriaxone, 256 μg/ml for Doxycycline, 2 μg/ml for Amoxiclav and 32μg/ml for Ciprofloxacin by tube dilution method. I recommend the population for strict following of the Islamic instructions in managing their sexual life, I recommend the medical staff to use remedies other than antibiotics in treating such a disease like natural remedies such as Fenugreek, Apple Cider Vinegar, raw honey, and others, and I recommend researchers to look for genes responsible for particular drug resistance. Top Keywords N. gonorrheae, antimicrobial resistance, herbal substitute. Top |