Intra-Articular Hyalronic Acid Injection Versus PRP Injection Regarding Cost-Effectiveness in Treatment of Osteoarthritis of the Knee (OAK) in Salah-Aden Province Ismaeel Tariq1, Mohammed Ali Abdulrazzaq, Hasan Adil Bdaiwi3, Mohammed Ali Abdulrazzaq2, Hasan Adil Bdaiwi3 1Department of Orthopedics, College of Medicine, Tikrit University, Salah Aldin 2Department of Orthopaedic, College of Medicine, University of Fallujah 3Department of Orthopaedic Surgery, Yarmook Teaching Hospital, Baghdad, Iraq Online published on 27 November, 2019. Abstract Background Osteoarthritis of the knee (OAK), that may be caused disability and decreasing the quality of life. Intra-articular injections can be provide relief from symptoms as platelet rich plasma(PRP) and hyaluronic acid (H.A)injection. Aim of current study is examining the cost-effectiveness of both (PRP and H.A) injection products in treatment the Osteoarthritis of the knee (OAK). The cost is a very important issue in areas where there is a large number of displaced people. Patient and Method 90 Patients with OAK, with age range (38–65) years, with a symptom of more than 1 year, diagnosis by X-ray (the Kellgren-Lawrence grade from 1–4), also done.45 patient given a hyaluronic acid injection and 45 patient given PRP the patient selected according to their socioeconomic status(patient who is financially capable were given a hyaluronic acid injection. The hyaluronic acid injection cost about 200$ while PRP cost 25$. the study was carried in a private clinic, the period from January 2017 to January 2018. The patient selected from people of Salah Aldin province were a large number of them were displaced from their places and were financially incapable. Results When compared, hyaluronic acid and PRP injection in OAK joint there were(non-significant difference) regarding clinical improvement, and outcome but the important difference is the cost of the injection (average 200$ for hyaluronic acid injection and 25$ for PRP injection) which significantly important regarding cost-effectiveness in areas of low financial income (special concern for areas where displacement occurred). Conclusion Results of current study showed that using PRP in OAK is more cost effective in areas of low income. Top Keywords Hyalronic acid, cost-effectiveness, osteoarthritis, knee, platelet rich plasma. Top |