Primary Papillary Serous Carcinoma of Cervix: A Rare Variant of Cervical Malignancy Lakshmi I Sree*, Associate Professor, Anunayi J, Associate Professor, Sreedhar VV, Professor, Khan Mohd Amanulla, Postgraduate Student, Sarigama M, Postgraduate Student Upgraded Department of Pathology, Osmania General Hospital, Hyderabad, India *Corresponding Author Email: sreelakshmi123@yahoo.co.in
Online published on 15 May, 2014. Abstract Papillary serous carcinoma of the uterine cervix is a very rare tumour, and is a recently described variant of cervical adenocarcinoma. It is an aggressive tumour with unpredictable course and poor prognosis. The incidence of cervical adenocarcinoma is 5–15%. This variant accounts for less than 50 cases in literature, has bimodal age distribution with one peak occurring less than 40 years and other occurring greater than 65 years age groups. Here, we present a 53 year-old woman presented with severe low backache and lump abdomen of 4 months duration. Per vaginal examination showed endophytic growth high up in the cervix. Pap smear and cervical biopsy done. Histopathological examination of cervical biopsy revealed papillary serous adenocarcinoma. Later, we received hysterectomy specimen with regional lymph nodes, which showed tumour limited to endocervix. Top Keywords Uterine cervix, Squamous cell carcinoma, Adenocarcinoma of endocervix, Immunohistochemistry, HPV. Top |