Keratocystic Odontogenic Tumour Admixed With Giant Cells: Case Report and Review on the Role of RANK/RANKL in its Pathogenesis Keerthana K.L.*, PG Student, Mounija, PG Student, Rajanikanth M., Professor Department of Oral Pathology, G. Pulla Reddy Dental College, G.P.R Nagar A.P. Nandyala Road, Kurnool-518007, Andhra Pradesh, India *Corresponding author email id: kheer9@gmail.com
Online published on 3 August, 2016. Abstract ‘Odontogenic keratocyst’ (OKC) was the term coined by Philipsen in the year 1956, while Pindborg and Hansen in the year 1963 described the details of this cyst[1,2]. OKC is renamed as keratocystic odontogenic tumour (KCOT) by WHO[3] taking into view its aggressive and recurrent nature. OKC arises from the rests of dental lamina[1]. It can occur anywhere in the oral cavity wherever the osseous structures are present, but most commonly in the posterior regions of the mandible[2,4]. Since the clinical and radiological profile of OKC mimics other lesions it may affect the appropriate diagnosis. Here we report a case of aggressive OKC which affected an entire quadrant of the mandible along with the ramus. Top Keywords Odontogenic keratocyst, Pathogenesis, Keratocystic odontogenic tumour. Top |