Assessment of Plasma Vitamin B12 and Folic Acid During Postmenopausal Period Tambe Deepak1, Gavali Sudhir2,*, Pranita A1, Kharche J. S.2, Godbole Gayatri1, Joshi Anuradha3 1Assistant Professor, Department of Physiology, Bharati Vidyapeeth (Deemed to be University) Medical College, Pune 2Associate Professor, Department of Physiology, Bharati Vidyapeeth (Deemed to be University) Medical College, Pune 3Professor & Head, Department of Physiology, Bharati Vidyapeeth (Deemed to be University) Medical College, Pune *Corresponding Author: Dr. Sudhir Gavali, 805, Neelam Apartments, Shree Mahalaxmi Nagar, Chaitraban, Bibwewadi, Pune-411037, Phone No.: 8796974215, e-mail: sudhirgavali0069@gmail.com
Online published on 21 November, 2019. Abstract Objective With increasing age and hormonal changes in life of women there is change in levels of micronutrients like vitamin B12 and folic acid. Very little data is available on the association between the basal levels of micronutrients such as VitB12, folic acid in pre and post menopausal women. Presence of an association will throw light on the role of micronutrients in prevention of CVS diseases in menopausal women. This would reinforce the role of micronutrients as a cheap viable option in the prevention of CVD in menopausal women. Method Plasma vitamin B12 and folic acid level were measured by radioimmunoassay in 60 pre and postmenopausal women. Results Vitamin B12 and folic acid concentrations were statistically significantly lower in postmenopausal group when compared to premenopausal group. (p value <0.005) Conclusion This study has provided baseline levels of folic acid and vitamin B12 with their association with menopause. This may be helpful for planning supplementation studies of the micronutrients. Top Keywords Vitamin B12, folic acid, Homocysteine, Menopause. Top |