Phytochemical Screening by FTIR Spectroscopic Analysis and Anti-Fungal Activity of Fruit Extract of Selected Medicinal Plant of Ruta graveolens Al-Shareefi Ekhlas1, Sahib Ahmed Hadi Abdal2, Hameed Imad Hadi3,* 1Department of Biology, College of Science for Women, University of Babylon, Hillah City, Iraq 2Ecological Sciences, AL-Qasim Green University, Hillah City, Iraq 3Biomedical Science Department University of Babylon, College of Nursing, Hillah City, Iraq *Corresponding author: Imad Hadi Hameed. Biomedical Science Department, University of Babylon, College of Nursing, Hillah city, Iraq; Phone number: 009647716150716; E-mail: imad_dna@yahoo.com
Online published on 21 February, 2019. Abstract Ruta graveolens (the common rue) has been used for various therapeutic purposes, including relief of rheumatism and treatment of circulatory disorder. The purpose of our research were analysis of the bioactive chemical compounds of selected medicinal plant of Ruta graveolens using fourier transform infrared spectrophotometer analysis and evaluation of anti-fungal activity. Thirteen bioactive compounds were identified in the methanolic extract of Ruta graveolens. The Fourier transform infrared spectrophotometer analysis of Ruta graveolens proved the presence of alkenes, alkanes, and alkyl halides which shows major peaks at 667.37, 873.75, 921.97, 1004.91, 1014.56, 1242.16, 1317.38, 1595.13, 1614.42, 2330.01, 2357.01, 3228.84 and 3282.84. In the current study, the anti-fungal activity of Ruta graveolens methanolic extract was evaluated by determining the zone of inhibition against fungi. Ruta graveolens was very highly active against Aspergillus fumigatus (5.39±0.21). Top Keywords Phytochemical screening, FTIR spectroscopic, Medicinal plant, Ruta graveolens. Top |