Indian Journal of Public Health Research & Development
Year : 2019, Volume : 10, Issue : 1
First page : ( 1107) Last page : ( 1112)
Print ISSN : 0976-0245. Online ISSN : 0976-5506.
Article DOI : 10.5958/0976-5506.2019.00210.9

The Study of Oral Microbiological Changes in non-Hodgkin Lymphoma Patients Receiving Chemotherapy

Hatim Faris Abed^1,*, Diajil Ameena Ryhan¹, Al-Mizraqchi Abbas S.¹

¹College of Dentistry, University of Baghdad>, Iraq

*Corresponding author: Faris Abed Hatim. College of dentistry, University of Baghdad, Iraq

Online published on 21 February, 2019.

Abstract

Lymphoma is a group of blood cell tumors that developed from lymphocytes. It is of two main types, Hodgkin and non-Hodgkin lymphoma. Non-Hodgkin's lymphoma is a diverse collection of an abnormal growth of lymphoid tissues and prevalence of which increased since three decades. It is varied in the behavior of presentation, response to different modalities treatment and prognosis. It frequently involves not only lymph nodes but also extended to extranodal areas. Aim of study: To study the microbial flora in the oral cavity of non-Hodgkin lymphoma patients undergoing chemotherapy and compare it with that of health looking control subjects. Sixty (60) persons were participated in this study; 30 Patients with non-Hodgkin lymphoma; 30 health looking control subjects. Oral microbial isolates were identified and the number of bacteria and yeast in swabs were also estimated for all study subjects. The predominant isolate was Streptococcus spp. in study groups. Pseudomonas spp. was significantly higher percentage in non-Hodgkin lymphoma patients compared to health looking control subjects. Mean viable count of oral bacteria and yeast was highly significant in NHL patients (110.05×10⁵ and 33.79×10³ CFU/ml respectively) compared to healthy looking control subjects (43.67×10⁵ and 7.80×10³ CFU/ml respectively).

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Keywords

Non-Hodgkin Lymphoma, Chemotherapy, Oral Microbiological Changes.

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