The Role of CYP17 Gene Expression Towards Imbalance of Estrogen and Progesterone Hormones at Luteal Phase in Marriageable Girls Bahrun Suriani1,2, As'ad Suryani3, Sinrang Wardihan4, Patellongi Ilhamjaya4, Herlianty5, Taherong Ferawati5, Mappaware Nasrudin Andi6 1Postgraduate Doctoral Program, Faculty of Medicine, Hasanuddin University, Makassar 2Nursing Program, STIK GIA Makassar, Makassar 3Department of clinical Nutrition, Faculty of Medicine, Hasanuddin University, Makassar 4Department of Physiology, Faculty of Medicine, Hasanuddin University, Makassar 5Midwifery Program, STIK GIA Makassar, Makassar 6Faculty of Medicine, Moslem University of Indonesia, Makassar Online published on 21 February, 2019. Abstract Background Menstruation process occurs on marriageable girls as an indication that ovary has been in function. One of the menstruation phases is known as luteal phase. At this phase, a kind of problems sometimes happens, like imbalance of estrogen and progesterone hormones. Both are steroid hormones. CYP17 is a crucial enzyme for biosynthesis of steroid. Research Purpose To identify the roles of CYP17 gene expression towards imbalance of estrogen and progesterone hormones at luteal phase in marriageable girls. Research Method Adopting non-experimental design using cross sectional approach to 40 samples. Conclusions There is role between CYP17 gene expression and estrogen hormone levels. There is role between CYP17 gene expression and progesterone hormone levels. There is role between CYP17 gene expression and imbalance of estrogen and progesterone hormone. Top Keywords CYP17, estrogen, progesterone, marriageable girls. Top |