Does Gluten Free Diet and Delay in Celiac Disease Diagnosis Affect Dental Caries and Salivary Oxidative Stress in Children? Al-Obaidi Zainab Qasim M.1,*, Radhi Nada Jafer MH.1 1Department of Pedodontics and Preventive Dentistry, College of Dentistry University of Baghdad, Baghdad, Iraq *Corresponding Author: Zainab Qasim M. Al-Obaidi, Department of Pedodontics and Preventive Dentistry, College of Dentistry, University of Baghdad, Baghdad, Iraq, Email: zainabobaidi1989@gmail.com
Online published on 23 December, 2019. Abstract Background Celiac disease, also named celiac sprue, is chronic malabsorption syndrome characterized by intestinal inflammatory reaction to dietary gluten in genetic susceptible individuals. The available treatment is by strict lifelong gluten free diet. The disease manifestations are not restricted intestinally but interestingly are often presented orally. Objective To assess the effects of gluten free diet and delay in celiac disease diagnosis in children on selected oral variables. Subjects and Method A case-control study was carries out in Baghdad including 20 newly diagnosed celiac disease children aged 7–11 years before initiation of gluten free diet (group A) and another 20 children committed to the diet (group B) compared to 40 children free from the disease (control group). Dental caries and salivary malondialdehyde were studied. Results Dental caries was lower in study groups than in control, there was no significant difference between delay in diagnosis and dental caries (P>0.05). Significant difference was found among study and control groups mean values concerning salivary malondialdehyde (Fisher exact = 114.200, P= 0.000). Significant difference was found between delay in diagnosis and salivary malondialdehyde level in the group committed to gluten free diet (T=2.124, P=0.048). Conclusion There was a relationship among celiac disease, gluten free diet, delay in diagnosis and salivary malondialdehyde. Dental caries was experienced at lower extent in celiac disease children. Top Keywords Celiac disease (CD), Gluten free diet (GFD), malondialdehyde (MDA), dental caries. Top |