Study the Inflammatory Biomarkers of Acute Coronary Syndrome Patients in Wasit Province AL-Rubaie Sama Ali1, R.S.AL-Attabi Mohammed1,*, AL-Kinani Alaa A.2 1Department of Biology, College of Science, Wasit University, Wasit, Iraq 2Al-Zahraa Teaching Hospital, Wasit Health Office, Ministry of Health and Ecology, Iraq *Corresponding Author: Mohammed R.S.AL-Attabi, Department of Biology, College of Science, Wasit University, Wasit, Iraq, Email: dr.mohammadrjy1@gmail.com
Online published on 23 December, 2019. Abstract This prospective study was performed in the coronary care unit at AL-Zahraa teaching hospital in Wasit Governorate during the period from January 2018 to June 2018. This study explained the role of inflammatory biomarkers in proper diagnosis, risk stratification and prognostic evaluation of patients with acute coronary syndrome (ACS). A total of 100 patients with ACS, 77 men aged 25–90 years and 23 women aged 45–85 years. They were divided into three age groups. The first group was ˂45years old, the second group was 45–60 years old and the third group was ˃60 years. The risk factors for ACS include gender, age, HT, diabetes, smoking, and dyslipidemia through a questionnaire. Our study revealed that male to female ratio was 3: 1 and demonstrate that male gender and HT were most prevalent risk factor for ACS. Regarding white blood cells and the rate of Erythrocyte sedimentation rate, the results showed a significant increase in white blood cells, neutrophils and the rate of red blood cell deposition at P≤0.05. The results of our study showed a significant increase in the markers of the acute phase protein, which showed a significant increase in the value of fibrinogen and C-reactive protein(CRP) at P≤0.05. Regarding biomarker of myocardial ischemia, there was a significant increase in troponin and creatinine kinase at P≤0.05. There was high 30 day mortality among patients with high level of inflammatory biomarker (fibrinogen and CRP), biomarkers of myocardial ischemia(troponin and CK-MB) and those with markedly elevated WBC count. Top Keywords ACS, Inflammatory, Biomarker. Top |