Changes in Freet3;T4 Thyroxine and Thyrotropin in Hemodialysis and Non-Dialysis Chronic Renal Failure Patients Kadhum Yasamin Abdul-Amer1, Asaad Dalal Abd Al-Sattar1,*, Sultan Ali Shalash1 1Biology Department, College of Science, Mustansiriyah University, Iraq *Corresponding Author: Dalal Abd Al-Sattar Asaad, Biology Department, College of Science, Mustansiriyah University, Iraq, Email: dully@uomustansiriyah.edu.iq
Online published on 23 December, 2019. Abstract The metabolism, degradation and excretion of thyroid hormones is associated with renal function. The study was aimed to evaluate the serum urea, creatinine and thyroid function in hemodialysis and non-dialysis patients. The levels of creatinine increased in non-dialysis. T3, FT3 and FT4 decreased in hemodialysis chronic renal failure, but T4 and TSH were within normal values. Materials and Method The serum urea, creatinine, (TT4), (FT4). (TT3), (FT3) and Thyrotropin (TSH) levels were estimated in serum 60 subjects with hemodialysis and non-dialysis in Baquba Teaching Hospital. They were divided into 2 groups as: Group 1 Containing 30 hemodialysis subjects (15 males, 15 females) and Group 2 containing 30 non-dialysis patients(15 males, 15 females). The levels of urea were measured by Urea-Kit called end point enzymatic method of urea concentration. Creatinine levels were measured by using creatinine kit methods. Results Hemodialysed subjects showed significant (P< 0.05) reduction in T3, FT4, FT3 and creatinine in comparison with non-dialysis subjects group. While Urea, TT4 and TSH valuesshowed non significant difference (p>0.05). Conclusion Total thyroxine and TSH don't effected in both groups of subjects. Top Keywords Chronic renal failure(CRF), Thyroid hormones. Top |