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Indian Journal of Public Health Research & Development
Year : 2019, Volume : 10, Issue : 10
First page : ( 2643) Last page : ( 2647)
Print ISSN : 0976-0245. Online ISSN : 0976-5506.
Article DOI : 10.5958/0976-5506.2019.03265.0

Comparison between WBCs, RBCs and HGHB Levels for Iraqi AML Patients Pre and Post 3-and 7-Treatment within Four Age Groups Segmented Based on Growth Levels

Imad Ishtar1,*, Ghaloub Abdulameer N.2, Ozaslan Mehemt3, Alwan Alaa F.4

1Ph. D Student, University of Mustansiriyah, Baghdad, Iraq

2Department of Biology, University of Mustansiriyah, Baghdad, Iraq

3Department of Biology, University of Gaziantep, Gaziantep, Turkey

4FICMS Internal Medicine, FICMS Clinical Hematology, The National Center of Hematology, Mustansiriyah University

*Corresponding Author: Ishtar Imad Majeed, Ph. D Student, University of Mustansiriyah, Baghdad, Iraq, Email: ishtar.imad@yahoo.com

Online published on 23 December, 2019.

Abstract

Background

Acue myeloid Leukemia is one of the rapidly progressing leukemia and it is diagnosed in all age groups (pediatrics, teens, adults, and geriatric group). In addition, most of physicians depend on complete blood count to evaluate whether the patients need bone marrow aspiration to be diagnosed for CD markers to determine type of leukemia. The aim of current study was to compare white blood cells, red blood cells and hemoglobin levels among Iraqi patients with acue myeloid leukemia.

Method

So a pool of 60 newly diagnosed patients segmented within 4 growth levels (0–15 years, 16–40 years, 4–65 years and 66-above) with 15 subjects in each segment. Complete blood counts done for them then another 60 samples were collected from the same patients a month after 3-and 7-treatment receiving. The comparison was done between growth levels from one side and treatment effect from another.

Results

The outcomes showed significant difference in white blood cells count within the same growth level between pre and post treatment patients (44.65 ± 8.51, 15.62 ± 2.83) for the 1st age group pre and post treatment, respectively (P˂0.05). Also, there were differences between age groups for the pre-treatment patients (44.65 ± 8.51, 29.03 ± 9.16, 8.35 ± 5.96 and 32.02 ± 6.06) for the four age groups, respectively, and the post treatment patients (1.95 ± 0.21, 3.16 ± 0.20, 5.77 ± 0.84, and 2.34 ± 0.23) for the four age groups, respectively. Red blood cells evaluation showed significant differences between pre and post treatment within the same age group (1.95 ± 0.21, 4.10 ± 0.17 for 1st age group) pre and post treatment, respectively, and within the same age group for pre and post treatment alone. Hemoglobin evaluation showed statistical differences between pre and post treatment samples within the same age group, but not between age groups.

Conclusion

White blood cells, red blood cells and hemoglobin evaluation give a primary reflection for AML patient`s status whether they improve or get worse.

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Keywords

AML, CBC, growth level, Platelet, MPV.

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