Role of Photodynamic Therapy in Endodontics-A Review Shuruthi Jagadeesh1,*, Malarvizhi Dhakshinamoorthy2, Mitthra Suresh3, Subbiya Arunajetasan4 1Second Year PG Student, Department of Conservative Dentistry and Endodontics, Sree Balaji Dental College and Hospital, Bharath Institute of Higher Education and Research, Narayanapuram, Pallikaranai, Chennai, Tamilnadu, India 2Professor, Department of Conservative Dentistry and Endodontics, Sree Balaji Dental College and Hospital, Bharath Institute of Higher Education and Research, Narayanapuram, Pallikaranai, Chennai, Tamilnadu, India 3Reader, Department of Conservative Dentistry and Endodontics, Sree Balaji Dental College and Hospital, Bharath Institute of Higher Education and Research, Narayanapuram, Pallikaranai, Chennai, Tamilnadu, India 4Professor and Head, Department of Conservative Dentistry and Endodontics, Sree Balaji Dental College and Hospital, Bharath Institute of Higher Education and Research, Narayanapuram, Pallikaranai, Chennai, Tamilnadu, India *Corresponding Author: Dr. Shuruthi Jagadeesh, M.D.S., Second Year Pg Student, Department of Conservative Dentistry and Endodontics, Sree Balaji Dental College and Hospital, Bharath Institute of Higher Education and Research, Narayanapuram, Pallikaranai, Chennai-600100, Tamilnadu, India, Phone: 6383230132 Email: jshuruthi24@gmail.com
Online published on 4 April, 2020. Abstract The irrigants used commonly do not always eradicate the entire microbial flora in infected root canals. Thus in quest other strategies, such as photodynamic therapy (PDT) have been developed. The word photodynamic means the applications of the dynamics of photons of light on the biological molecules. German physician Friedreich Mayer performed the first study, which was first called as photo-radiation therapy with porphyrins (1913) in humans. Photoactivated disinfection is based primarly on the interaction of a photosensitive antibacterial agent and a light source which uses a nontoxic dye named photosensitizer (PS) and lowintensity visible light. In the presence of oxygen, these combine to produce some cytotoxic species. The PS molecules attach to the bacteria membrane. Irradiation with a specific wavelength of the light may result in the production of singlet oxygen, resulting in rupture of the microbial cell wall. There are several applications for PDT in dentistry.. Photodynamic therapy has also been used to disinfect caries dentin before the restoration, disinfecting oral tissues before or during surgical procedures, treating denture stomatitis, and treating oral candidiasis in immunocompromised patients. Photodynamic therapy can also be used in combination with mechanical instrumentation and chemical antimicrobial agents, such as sodium hypochlorite. Top Keywords Photodynamic, biofilm, endotoxin, irrigants. Top |