Clinical and Molecular Profile of Patients with Breast Cancer in Tikrit Province Ali Ali Abbas Samarra General Hospital, Ministry of Health, Iraq Online published on 8 March, 2019. Abstract Background breast cancer is the most frequently diagnosed cancer and the leading cause of cancer death in women, a good description of the patients’ clinical and molecular characteristics is essential to better understanding of the disease. Patients and Method A retrospective study that included 79 patients diagnosed with breast cancer, the study carried out during the period of 1st January 2014 to 1st December 2015. The aim of the study Evaluate the patients’ clinical profile and molecular profile for females with breast cancer. Results Mean age of the patients was 52.9 ± 10.1 years and the BMI was 28.8 ± 4.7 kg/m2, 73.4% ER positive, 70.9% with PR positive, and 24.1% Her2 positive. T-staging was 13.9%, 57.0%, 25.3% and 3.8% (T1 to T4 respectively) while N-staging was 32.9%, 39.2%, 10.1% and 17.7% (N0 to N3 respectively). Conclusion The clinical and molecular profile of Iraqi women patients with breast cancer was similar to reported in the literature, with mean age at diagnosis in the six decade, 73.4% ER positive, 70.9% with PR positive, and 24.1% Her2 positive. Top Keywords Age, estrogen receptor, progesterone receptor, her2, Iraq. Top |