Evaluation of Platelet Rich Fibrin Effect in the Bone Density after Teeth Extraction by Cone Beam Computed Tomography Mezal Kamal Saheb1,*, Al-Adili Sahar Shakir2, Al-Haddad Ali S.2 1Ministry of Health, Karbala Hospital, Karbala, Iraq 2College of Dentistry, University of Baghdad, Baghdad, Iraq *Corresponding author: Kamal Saheb Mezal, Phone number: +964 782 567 8332, Email: dr.kemalsh@gmail.com
Online published on 6 April, 2019. Abstract Background Platelet Rich Fibrin (PRF) favors the development of microvascularization and is able to guide epithelial cell migration to its surface. This material acts as a biodegradable scaffold that consists of an autologous leukocyte-platelet-rich fibrin matrix composed of a tetra molecular structure, with cytokines, platelets, cytokines and stem cells within it. This work hypothesis is that the platelet rich fibrin increase the bone density after teeth extraction. Objective Examine the role of platelet rich fibrin in healing of extraction socket. Method 36 participants with an age range from 20– 52 years old. The participants divided into two groups, the study group was treated with PRF in the socket after teeth extraction while the control group conducted without PRF. Both groups had simple non-traumatic teeth extraction. The preparation of the PRF include 5 ml of blood centrifuged at 3000 rpm for 10 min, then gently sutured the socket after putting the PRF clot to minimize the suturing effect on the healing process. After 4 months, the new-bone density formed in the socket was measured by Cone beam computed tomography (CBCT). Result Maximum and mean density was significantly higher in the study group compared to control‎, the bone density in upper jaw was significantly higher in study group compared to control, the bone density in upper jaw was significantly higher in study group compared to control. Conclusion Platelet Rich Fibrin show better healing effect and increase in bone density compared to standard of care Top Keywords Platelet rich fibrin, CBCT, done density, teeth extraction, jaw. Top |