Indian Journal of Public Health Research & Development
Year : 2019, Volume : 10, Issue : 4
First page : ( 490) Last page : ( 495)
Print ISSN : 0976-0245. Online ISSN : 0976-5506.
Article DOI : 10.5958/0976-5506.2019.00744.7

Evaluation of the Effects of Insulin Therapy on peripheral Nervous System in Diabetic Patients

Taha Mufeed Akram*

MBChB, FIBMS Neurology, Department of Medicine, College of Medicine, University of Kirkuk-Iraq

*Coresponding author: Mufeed Akram Taha, email: mofeedakram@yahoo.com

Online published on 6 April, 2019.

Abstract

Peripheral neuropathy is common diabetic complication that associated with high rates of morbidity and mortality. Insulin therapy is essential in treatment of diabetic peripheral neuropathy; however, rapid strict glycemic control may lead to many complications such as neuropathy. This study performed to evaluate the effect of insulin therapy on peripheral nervous system in patients with type 2 diabetes. This study was conducted in outpatient clinics of Neurology departments of “Azadi Teaching Hospital in Kirkuk city-Iraq” during the period from the 1^st of October, 2015 to 30^th of September, 2017 included 50 type 2 diabetic patients treated with insulin therapy. Patients followed up at 3^rd and 6^th months after first examination by evaluating fasting blood sugar, hemoglobin A1c, Toronto scoring and nerve conduction study. Findings revealed predominance of females. There was a significant decline in overnight fasting blood sugar and hemoglobin A1c levels after 6 months follow up (p<0.001). The mean Toronto score increased from 5.9 at baseline to 10.6 after 3 months and 12.1 after 6 months. In conclusion the rapid strict glycemic control of blood sugar level is obviously considered to be a risk factor for peripheral neuropathy development among type 2 diabetic patients.

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Keywords

Type 2 diabetes mellitus, Insulin treatment, Peripheral neuropathy.

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