Cholesterol and Triglyceride Indices Are Linked to the Left Ventricle Diastolic Dysfunction: An Echocardiography and Tissue Doppler Study Ghazi Suaad Muhssen1,*, Hussain Ismail Ibrahim1, Adil Aalaa Saad1 1College of Medicine, Al-Mustansiriyah University, Iraq *Corresponding author: Suaad Muhssen Ghazi, E-mail: suad94@ymail.com
Online published on 30 April, 2019. Abstract Echocardiography and tissue Doppler are non-invasive technique that used to detect the subclinical abnormalities of the myocardial function in diabetic patients. Determination of the lipid indices and the parameters of the left ventricle function by using conventional and tissue Doppler in asymptomatic T2D patients. This cross-sectional study included 39 healthy subjects (Group I) and 28 patients with type 2 Diabetes (Group II). The measurements of the blood pressure, anthropometric variables and fasting lipid profile were determined. The cardiac function was determined by using conventional and tissue Doppler echocardiography. Group II expressed significantly high values of anthropometric measurements, and diastolic blood pressure, and a low value of high density lipoprotein. Significantly high values of E/é (medial annulus), E/é (lateral annulus) and É/Á (medial annulus) were observed in Group II compared with Group I. The area of the under the curve of E/A, É/Á (lateral annulus), É/Á (medial annulus) ratios were significantly higher in Group II compared with Group I (0.640 versus 0.385; 0.610 versus 0.259; 0.668 versus 0.396, respectively) when the cholesterol index >1. The area of the under the curve of E/é (lateral annulus) ratio and left ventricular mass were significantly higher in Group II compared with Group I (0.533 versus 0.299; 0.561 versus 0.230, respectively) when the triglyceride index >1. We conclude that the determinants of the diastolic left ventricle dysfunction which that detected by conventional and/or tissue Doppler in T2D are associated with high cholesterol and triglyceride indices which may serve as discriminator markers. Top Keywords Cholesterol index, Triglyceride index, Echocardiography, Tissue Doppler, type 2 Diabetes. Top |