A Comparison Study among Several Tumor Markers in Serum Samples of Patients with Colon Cancers Jasim Rasha Hasan* Department of Chemistry, Faculty of Education for Girls, University of Kufa, Iraq *Corresponding author: Rasha Hasan Jasim, E-mail: dr.rashahussainee@yahoo.comprovince
Online published on 30 April, 2019. Abstract During six years ago, 109 patients with malignant colon cancers at metastasis stages (II to IV stages), 112 patients “as a pathological control group”, and 85 healthy individuals were enrolled in the present work. CLEC4E, CEA, CA 19-9, and Serotonin levels were measured in the sera of study individuals using sandwich ELISA technique. Current study demonstrated significant increase in the levels of CLEC4E, CEA, and CA 19-9 in the malignant colorectal cancers comparison to pathological controls as well as healthy individuals. Serotonin levels were seemed to be lower at cancerous patients comparison to healthy controls. CLEC4E may be used as a definitive diagnostic marker for cancers than other nonmalignant diseases, moreover CLEC4E and serotonin can be considered as new diagnostic tools for colon cancer and are highly effective follow-up tools and can be diagnostic and follow-up tools when measured with other resident parameters. Measured parameters (CLEC4E, CEA, CA19-9, and Serotonin) can be effective screening tools when diagnosing tumor infections in the colon. Top Keywords CLEC4E, CEA, CA 19-9, Serotonin, Colorectal. Top |