Study of Programme related Influencing risk Factors on Multidrug resistance Tuberculosis: A case control Study from Western Maharashtra Kumar Vikash1,*, raje Vaishali V.2, Kakade Satish V.3, Durgawale Prakash M.4 1Tutor, Department of Community Medicine, Krishna Institute of Medical Sciences, Karad, Maharashtra, India 2Professor, Department of Community Medicine, Krishna Institute of Medical Sciences, Karad, Maharashtra, India 3Statistician cum Associate Professor, Department of Community Medicine, Krishna Institute of Medical Sciences, Karad, Maharashtra, India 4Professor & HOD, Department of Community Medicine, Krishna Institute of Medical Sciences, Karad, Maharashtra, India *Corresponding Author: Dr. Vikash Kumar, Department of Community Medicine, Krishna Institute of Medical Sciences, Karad, Maharashtra (India)-415539, Phone: +91-7038443522, Email: vikashanmmch@gmail.com
Online published on 4 June, 2019. Abstract Background Multidrug Resistance Tuberculosis (MDR-TB) an emerging and a growing threat to tuberculosis control program all over the world. This problem is of special concern because second-line drugs required for its treatment are often unavailable, are far more expensive than the first-line drugs, with only 65–75% efficacy, and have side effects that may require hospitalization. The reasons quoted for the same was inconsistent and or interrupted drug intake or supply. Objectives To study programme related variables present in Multidrug Resistance Tuberculosis cases. Materials and Method This case-control study was carried out for the assessment of programme related influencing factors for Multidrug Resistance Tuberculosis among TB patients enrolled for DOTS under RNTCP during the period of 2016 to 2018 at various sub-district levels. Results Majority of MDR cases (96.2%) were visited by senior tuberculosis supervisor, and 98.1% by DOTS providers. Among treatment profile 98.1% MDR patient were on categories II in which relapse (57.8%), treatment failure (33.3%) and default were 8.8%. High proportion of sputum samples were sent to Designated Microscopy centre (51.9%) at grass root level followed by Districts Tuberculosis center (18.3%) and at Tuberculosis unit (16.3%). Most patients (78.8% cases) lived at a distance less than 2.5 kilometer from DOTS provider. Conclusion If the guideline given by the Revised National Tuberculosis Control programme is implemented smoothly at the level of District then there would not be any program based reason to develop resistance to primary anti tubercular drugs. Top Keywords Multidrug Resistant Tuberculosis, RNTCP, Influencing factors, Programme. Top |