Evaluation of Hematological and biochemical Parameters in Dengue Nayak Kusumakshi1, Patil Asha1,*, Shetty Ramya2, D'Souza Shaila2, Nayak M Deepak3 1Assistant Professor, Department of Medical Laboratory Technology, School of Allied Health Sciences 2UG Intern, Department of Medical Laboratory Technology, School of Allied Health Sciences 3Associate Professor, Department of Pathology, Kasturba Medical College, Manipal Academy of Higher Education, Manipal *Corresponding Author: Ms. Asha Patil Assistant Professor-Selection Grade School of Allied Health Sciences Manipal Academy of Higher Education, Manipal, Email: asha.patil@manipal.edu
Online published on 4 June, 2019. Abstract Background Dengue is one of the most common arboviral infection in the world. Evaluation of the clinical parameters for the early diagnosis of the disease is used to assist the preventive strategies. This study aimed to evaluate the hematological and biochemical parameters retrospectively in patients with serologically confirmed dengue infection over a one-year period. Method The study was conducted in clinical laboratories of a tertiary care hospital serving the people of Karnataka and neighbouring states. A retrospective analysis of known IgM and anti-NS1 seropositive dengue patients over a period of one year was done to evaluate the hematological and biochemical data for any significant variations. Results A total of 108 patients were studied. 100 (92.60%) patients had Dengue Fever, 4 (3.70%) had Dengue haemorrhagic Fever, and 4 (3.70%) had Dengue Shock Syndrome. Thrombocytopenia in 87 (80.60%) cases, elevated AST in 92 (85.2%) and raised CK/CPK level observed in 50% of the cases. Conclusion The alterations in hematological and biochemical parameters is associated with the patient case history and the clinical diagnosis. Top Keywords Dengue, arboviral infection, hemorrhagic fever, platelet count, hematological parameter. Top |