Comparison of ACPA and Anti RA33Ab as Prognostic Factors in Patients with rheumatoid Arthritis Alattabi Alaa S.1, Jaber Murtada A. Abood2, Zenki Firas A.3 1Assist Professor, College of Medicine University of Karbala, Department of Medical Microbiology & Immunology, Kerbala, Iraq 2MSC Student, College of Medicine, University of Karbala, Department of Medical Microbiology & Immunology, Kerbala, Iraq 3MSC, Rheumatologist, Imam Hussain Medical City, Rheumatology Unit, Kerbala, Iraq Online published on 4 June, 2019. Abstract Background The Anti RA33Ab and ACPA are high specific Abs for RA disorder, ACPA associated with more erosive disorder and Anti. RA33Ab with less erosive and has good prognostic factor character. Objective Comparisons Anti RA33Ab and ACPA level in rheumatoid arthritis patients and correlation with disease activity. Method Case-Control Study included patients attended Imam Husain medical City/Rheumatology Department at a period from December-2017 till April-2018, the study included180 patient and 180 control all patients were diagnosed according to ACR2010-criteria by rheumatologist, permission had been taken from all subjects, venous blood sample had been taken for ESR(westergreen method), CRP, RF(semiautomated Genrui AP54 specific protein analyzer), ACPA&AntiRA33Ab(ELISA). Results Mean level of AntiRA33Ab in mild, moderate and sever groups of patients 11.97 ± 0.21, 10.71 ± 0.10 and 9.26 ± 0.15 respectively while ACPA (U/ml) level in mild, moderate and sever groups of patients 68.40 ± 14.60, 107.82 ± 22.45 and 160.0 ± 30.51 respectively. Conclusion The AntiRA33Ab can be used as prognostic markers for RA patients and disease controlling and correlated with less sever RA cases. Top Keywords DAS, anti RA33Ab, ACPA. Top |