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Indian Journal of Public Health Research & Development
Year : 2019, Volume : 10, Issue : 5
First page : ( 1048) Last page : ( 1051)
Print ISSN : 0976-0245. Online ISSN : 0976-5506.
Article DOI : 10.5958/0976-5506.2019.01225.7

Correlation of Serum Copper, Zinc, Magnesium with Insulin Resistance in Pcosfemale of Reproductive Age Group

Revathi R1, Julius A.2, Singaravelu Swetha3

1Research Scholar, Bharath Institute of Higher Education and Research, Selaiyur, Chennai

2Professor and Head, Department of Biochemistry, Sree Balaji Dental College, Bharath University, Pallikaranai, Chennai

3Junior Consultant, Apollo Hospital, Chennai

Online published on 4 June, 2019.

Abstract

Background

Insulin resistance is communal in patients with PCOS-Polycystic Ovary Syndrome. Serum copper, zinc, magnesium are measured and it is correlatedwith insulin resistance.

Aim of Study

The present study intended to determine correlations among insulin Resistance and minerals like copper, zinc, magnesium inpatients with PCOS.

Methodology

The subjects were identified from gynecology OPD of private medical college in Tamilnadu. The study involved 200 femaleof age 15–45 years (100female had PCOS and the other 100 female werecontrols).

Results

HOMA wasmeaningfully higher in female with PCOS in contrast with Control. There was a significant correlation of copper, zinc and magnesium with insulin resistance. It was observed that the levels of copper and zinc increases with patient showing insulin resistance while magnesium was lowered in the same.

Conclusion

There is a significant correlation between the levels of copper, zinc, magnesium and IR in patients with PCOS.

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Keywords

Copper, zinc, magnesium, HOMAIR, PCOS.

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