Correlation of Glycated Hemoglobin (Hba1c) and Serum Uric Acid in Type-2 Diabetic Patients Fadhe Alaa Abbas*, Yousif Ahmed Kadhim Al-Mussaib Technical College, Al-Furat Al-Awsat Technical University, Babylon, Iraq *Corresponding author: Alaa Abbas Fadhe, E-mail: Alhaddad2011@yahoo.com
Online published on 4 June, 2019. Abstract Type-2 diabetes mellitus (DM) is a metabolic disorder identified as chronic hyperglycemia with disturbance of carbohydrate, protein and fat caused by defects in insulin action and/or secretion. This study was designed to determine the relationship between glycated hemoglobin (HbA1c) and serum uric acid (SUA) for type-2 diabetic patients. the study was performed on forty-eight patients (58 ± 14 years old) and thirty-nine healthy individuals matched the sex, and age with patients (control group). Fasting blood samples were collected from both groups. Fasting blood sugar (FBS), SUA concentration, HbA1c level, total protein (TP), cholesterol, and triglyceride (TG) were measured and investigated. The obtained results showed that there is a significant positive correlation (r= +0.103, p= 0.04) between HbA1c and SUA for patients group. As well as significant positive correlations with FBS (r= + 0.410), TG (r= +0.305), TP (r=+0.322), and cholesterol (r=+0.23). Comparison study was also performed between patients and healthy subjects and the results showed a significant elevation for SUA, TG, cholesterol, TP, FSB, and HbA1c for the patients in type-2 diabetes compared with healthy subjects. The current study confirms serum uric acid level acts as a biomarker of blood glucose and has an adverse effect on glycemic control in type-2 diabetic patients. Top Keywords Type-2 diabetes, Serum Uric acid, HbA1c. Top |