Evaluation of Polycystic Ovarian Syndrome Women as a Result of Clomiphene Treatment Naji Zainab Abdul wahed* MSc, Clinical Biochemistry, Al Iraqia University, Baghdad, Iraq *Corresponding Author: Zainab Abdul Wahed Naji, MSc, Clinical Biochemistry, Al Iraqia University, Baghdad, Iraq, Phone: 07700126197, Email: zainabnaji2@gmail.com
Online published on 19 August, 2019. Abstract Polycystic ovary syndrome (PCOS) is a disorder that affects a woman's hormone levels Clomiphene citrate is used generally as an initial treatment. In the present study, LH, FSH, testosterone, progesteron and oestrogen were analysed for the women undergoing clomiphene in Iraq. Total 73 infertile PCOS women (age ranging from 19–33) were enrolled in the study and they were divided into 3 groups depending on the clomiphene treatment where, group 1 patients (n=21) were given 50mg, group 2 (n=23) were given 100mg and group 3 (n=28) were given 150mg dose of clomiphene. The serum leutinizing hormone and testosterone found to be decreased after treatment, while follicle stimulating hormone and estrogen showed the opposite trend. When various parameters are studied such as ovary size, number of follicles, endometrium layer, it was found that, ovarian size after treatment they are decreased but did not show any significant difference. Top Keywords Polycystic ovary syndrome, clomiphene, leutinizing hormone, testosterone. Top |