Multiple Major Aphthous Ulcers: An Uncommon Presentation Misra Satya Ranjan* Professor & Head, Department of Oral Medicine & Radiology, Institute of Dental Sciences, Siksha ‘O’ Anusandhan (Deemed to be University), Bhubaneswar, Odisha, India *Corresponding Author Satya Ranjan Misra, Professor & Head, Department of Oral Medicine & Radiology, Institute of Dental Sciences, Siksha ‘O ’Anusandhan (Deemed to be University), Bhubaneswar, Odisha, India, e-mail: satyamisra@soa.ac.in
Online published on 13 November, 2019. Abstract Aphthous ulcers or Recurrent aphthous stomatitis (RAS) are the most common ulcers encountered in the oral cavity and also the most painful ones. They characteristically recur at frequent intervals hence referred to as RAS. The aetiology of RAS is unknown however a number of predisposing factors including genetic predisposition, stress, nutritional deficiencies, diet, trauma, hormonal disturbances and immunological disorders have been proposed. As the cause remains uncertain, a definitive cure for the disease has not been found and all treatments are aimed at ameliorating the disease symptoms. They are of 3 sub-types: Minor, Major and Herpetiform. Major aphthous ulcers occur less commonly and are usually more than 10mm in size, fewer in number, healing with scarring. We present a case of multiple major aphthous ulcers in an immune-competent patient successfully treated with topical glucocorticoids and amlexanox with systemically administered Levamisole. Top Keywords Aphthous ulcer, immune competent, immunomodulators, unknown etiology. Top |