The effects of cold compress and warm compress on β-endorphin levels, IL-6 and TNFα among adolescent with dysmenorrhea Mukhoirotin1,*, Kurniawati1, Fatmawati Diah Ayu1 1Faculty of Health Science, University of Pesantren Tinggi Darul Ulum Jombang *Corresponding Author: Mukhoirotin E-mail: mukhoirotin@fik.unipdu.ac.id, University of Pesantren Tinggi Darul Ulum Jombang, Indonesia
Online published on 9 January, 2019. Abstract Non-pharmacological efforts to treat dysmenorrhoea are include cold compresses and warm compresses. The aim of this study was to determine the differences effect of cold compresses and warm compresses to β-Endorphin levels, IL-6 and TNFα among adolescents with dysmenorrhoea. The research was Post Test Only with Control Group. β endorphin, IL-6 and TNFα were measured by ELISA, then analyzed by Independent Sample T-Test. The average β level of Endorphin in cold compress group was 143.03 pg/ml, in warm compress group was 171.43 pg/ml; the average IL6 level in cold compress group was 1352.60 pg/ml, in warm compress group was 961.14 pg/ml and the average TNFα level in cold compress group was 345.75 pg/ml, in warm compress group was 262.50 pg/ml. The results of Independent Sample T-Test showed that there was no difference in β levels of Endorphin IL-6 and TNFα in both of the warm and cold compresses group. Cold compress and warm compress can stimulate loose of Endorphin β levels and regulate uterine hypercontractility during menstrual pain. Cold compress and warm compress can be used as an alternative to treat dysmenorrhoea. Top Keywords Cold compress, Warm compress, β-Endorphin levels, IL-6 levels, TNFα levels. Top |