Liver function and some biochemical parameters affected by anabolic androgen steroids and diet supplements consuming Jabbar Enas Abdul Kareem1, Jouda Jamela2,*,*, Abdulhussein Haider Sabah1, AL-Aboody Bassad A.1 1Department of Biology, College of Science, University of Thi Qar, Iraq 2Department of Biology, College of Science, Mustansiriyah University, Bagdad, Iraq *Corresponding author: Jamela Jouda Department of Biology, College of Science, Mustansiriyah University, Bagdad, Iraq. jamela.jouda@uomustansiriyah.idu.iq
Online published on 9 January, 2019. Abstract This study aims to evaluating the possible effect of anabolic androgen steroids (AAS) and diet supplements DS consuming by bodybuilders on their liver function and some biochemical parameters depending on consuming period. Blood samples were collected from 20 men didn't play any sport and 82 sport men who divided to four groups: 20 bodybuilder men consuming AAS, 20 consuming DS, 20 without consuming, and 22 football players. BMI of the subjects were also calculated. BMI and The frequency of overweight were significant higher in bodybuilder consuming AAS compared to other groups. Total and direct serum billirubin was significant higher in football player than bodybuilder consuming AAS and DS. The total bilirubin was also significant higher in football player than non sport men. While Alkaline Phosphate (ALKP) level was significant lower, Aspartate transaminase AST and Alanine transaminase (ALT) level were significant higher in serum of bodybuilder consuming AAS. Furthermore, their levels in bodybuilder consuming diet supplement were significant higher than non sport. No differences in ultra high-density lipoproteins (UHDL) and Cholesterol (Chol) levels were detected while Trig level was significant lower in serum of football player. Triglyceride (Trig) level was also significant lower in the serum of bodybuilder without consuming than consuming AAS. The differences of these parameters were studied in Bodybuilder consuming AAS and diet supplement groups in three consuming period: less 1 year, 1 to 2 years, and more than 2 years. No differences between the two groups after consuming period less than 1yr and 1-2yr while significant higher in bodybuilder consuming AAS after more than 2yr compared to consuming supplement were detected. As conclusion, both AAS and protein supplements have side effects on the liver function and other biochemical parameters and these effects increase with the consuming period especially the effects of AAS. Top Keywords AST, ALT, AAS, ALKP, billirubin. Top |