The status of lipid peroxidation system in erysipelas patients on the background of diabetes mellitus Marjokhova Madina1,*, Afashagova Marina2, Marjokhova Asiat3, Nagoeva Maryana4, Ivanova Marina5, Nalchikova Marina6, Tagirova Zarema7 1Head of the Department Department of infectious diseases, Kabardino-Balkarian State University, Nalchik, Russia 2Associate Professor, Department of infectious diseases, Kabardino-Balkarian State University, Nalchik, Russia 3Assistant Professor, Department of infectious diseases, Kabardino-Balkarian State University, Nalchik, Russia 4Professor, Department of infectious diseases, Kabardino-Balkarian State University, Nalchik, Russia 5Professor, Department of infectious diseases, Kabardino-Balkarian State University, Nalchik, Russia 6Associate Professor Department of infectious diseases, Kabardino-Balkarian State University, Nalchik, Russia 7Assistant Professor, Department of Infectious Diseases, Dagestan State Medical University, Makhachkala, Russia *Corresponding Author: Madina Marjokhova, Department of infectious diseases, Kabardino-Balkarian state University, Nalchik, Russia (Chernyshevsky st., 173; 360004). Email address: mmarjokhova@yahoo.com
Online published on 9 January, 2019. Abstract Background The erysipelas develops quite rapidly. This infectious disease is characterized by skin inflammation caused by streptococcus. Its progressiveness depends on many factors. The presence of diabetes occupying a leading place in the system of vascular events is one of the most significant factors. In this regard, this article studies the status of a lipid peroxidation system in erysipelas patients on the background of diabetes mellitus. Method The experiment was conducted in the Center for Prevention and Control of AIDS and Infectious Diseases (Kabardino-Balkar Republic, Nalchik city). There were two groups participating in the experiment: the first group consisted of 20 erysipelas patients; the second one-of 14 patients, whose erysipelas developed on the background of diabetes mellitus. All patients were taking tablets. Result As a result of the experiment, it turned out that lipid peroxidation occurs in biological membranes during the period of erysipelas. This is manifested by an increase in blood MDA level, as well as by a deficit of antioxidant protection and a decrease in the plasma antioxidant (ceruloplasmin). Conclusion Recorded changes in considered parameters were more pronounced and returned to normal after treatment on the unfavorable premorbid background-such a serious disease as diabetes mellitus. Top Keywords Ergotism (St. Anthony's fire), diabetes mellitus, antioxidant system, ceruloplasmin level, endointoxication. Top |