Surveillance of Microorganisms and Their Drug Sensitivity Patterns in Diabetic UTI Patient at a Tertiary Care Teaching Hospital Das Moumita1, Sahoo Swayamprabha1, Behera Ishwar Chandra2, Dhar Srikant Kumar3, Sahu Mahesh Chandra4,* 1Research Scholar, Medical Research Laboratory IMS and SUM Hospital, Siksha O Anusandhan Deemed to be University, K8, Kalinga Nagar, Bhubaneswar, Odisha, India 2Professor, Department of Community Medicine, IMS and SUM Hospital, Siksha O Anusandhan Deemed to be University, K8, Kalinga Nagar, Bhubaneswar, Odisha, India 3Professor, Department of Medicine, IMS and SUM Hospital, Siksha O Anusandhan Deemed to be University, K8, Kalinga Nagar, Bhubaneswar, Odisha, India 4Assistant Professor, Medical Research Laboratory IMS and SUM Hospital, Siksha O Anusandhan Deemed to be University, K8, Kalinga Nagar, Bhubaneswar, Odisha, India *Corresponding Author: Dr. Mahesh Chandra Sahu, PhD, NPDF, Assistant Professor, Medical Research Laboratory, IMS and SUM hospital, Bhubaneswar, Email: mchsahu@gmail.com
Online published on 2 February, 2019. Abstract Background Urinary Tract Infection (UTI) is one of the common infections affecting people, both from the community and hospital. The causative pathogens for UTI and their drug sensitivity patterns vary from region to region. Changes in their genetic constutients with time might be the reason. Aim In this study, we aimed investigate the profile of common uropathogens and assess their antibiotic sensitivity patterns with commonly used drugs for UTI patients. Materials and Method In this study, 153 urine samples were analyzed with routine microscopy, culture and sensitivity for a period of six months at Institute of Medical Science and SUM Hospital, Bhubaneshwar, Odisha. Both bacteria and fungi were used for drug sensitivity test. Result A total no. of 54Gram positive bacteria and 40 Gram Negative bacteria were isolated. S. aureus was the most common GPC isolated and P. aeruginosa was the most common GNB. E. coli was the second most GNB which showed resistance to Cephalosporins and Aminicoumarin group. 4 Candida species were isolated, to which Clotrimazole was the most succeptible antifungal agent. Staphyloccous sp showed resistance to β-lactams and Macrolids group of antibiotics. Shigella sp showed resistance to β-lactams. C. albicans was found to be the common Fungi isolated, followed by C. krusei. Conclusion Since the drug sensitivity pattern changes from place to place and varies from time to time. The culture sensitivity therapy should be practiced before empherical administration of antibiotics. Top Keywords Diabetes, Drug resistance, Candida, Oxacilllin, Bacteria. Top |