Biomarker for Evaluating Peripheral Vertigo-A Study at a Tertiary Care Teaching Hospital of Eastern India Swain Santosh Kumar1,*, Samal Smrutipragnya2, Sahu Mahesh Chandra3, Debta Priyanka4 1Professor, Department of Otorhinolaryngology, IMS and SUM hospital, Siksha “O” Anusandhan University, K8, Kalinganagar, Bhubaneswar, Odisha, India 2Research Scholar, Department of Otorhinolaryngology, IMS and SUM hospital, Siksha “O” Anusandhan University, K8, Kalinganagar, Bhubaneswar, Odisha, India 3Assistant Professor, Medical Research Laboratory IMS and SUM hospital, Siksha “O” Anusandhan University, K8, Kalinganagar, Bhubaneswar, Odisha, India 4Associate Professor, Department of Oral Pathology & Microbiology, I.D.S., Siksha “O” Anusandhan, Deemed to be university, BBSR, Odisha, India *Corresponding Author: Santosh K. Swain, Professor, Dept.of Otorhinolaryngology, IMS & SUM Hospital, Kalinga Nagar, Bhubaneswar-3, Odisha, India. Phone: +91-9556524887. Email: santoshvoltaire@yahoo.co.in
Online published on 2 February, 2019. Abstract Aim To investigate the relationship between peripheral vertigo to neutrophil to lymphocyte ratio (NLR) as an inflammatory marker. Materials and Method We had taken 68 patients with peripheral vertigo those attended the Otolaryngology department during January 2014 to October 2016. The systemic diseases, malignancy, neurological diseases or any inflammations in the body were excluded from our study. We recruited 68 healthy subjects those came to the hospital for routine health check up. Detail neuro-otological examination and audiological tests were done to rule out peripheral vertigo. Results Neutrophil to lymphocyte count was calculated in all cases and a comparison done between the vertigo patients and control groups. The mean NLR was statistically significant among the patients of peripheral vertigo than control groups (P=0.0021). There were no stastically significant between patients and control groups when comparing white blood cell count, hemoglobin, mean platelet volume, lipid profile, liver function tests. Conclusion NLR is higher among peripheral vertigo and it is stastically significant among patients than control groups. NLR is a potential marker in vertigo with peripheral origin. Top Keywords Peripheral vertigo, biomarker, neutrophil to lymphocyte ratio (NLR), inflammation. Top |