Using GC-MS Technique for Analysis of Bioactive Chemical Compounds of Penicillium Italicum and Determination of its Anti-Microbial Activity Mohammed Ghaidaa Jihadi1, Al-Rubaye Abeer Fauzi2, Hameed Imad Hadi3 1Department of Biology, College of Science, University of Al-Qadisiyah, Hillah City, Iraq 2Department of Biology, College of Science for women, University of Babylon, Hillah City, Iraq 3Biomedical Science Department, University of Babylon, College of Nursing, Hillah City, Iraq Online published on 3 April, 2018. Abstract The aims of our study were analysis of the bioactive chemical products and determination of antibacterial activity. Twenty eight bioactive compounds were identified in the methanolic extract of Penicillium italicum. The identification of bioactive chemical compounds is based on the peak area, retention time molecular weight and molecular formula. The results of anti-fungal and anti-bacterial activity produced by Penicillium italicum showed that the volatile compounds were highly effective to suppress the growth of Aspergillus terreus 6.302±0.20 mm and Proteus mirabilis 6.08±0.21 mm. In agar well diffusion method the selected medicinal plants were effective against Penicillium italicum. Melissa officinalis was very highly antifungal activity 6.70±0.25 mm. Top Keywords Anti-Microbial, Bioactive Chemical Compounds, GC-MS, Penicillium italicum. Top |