Characterization of Antibacterial and Antifungal Metabolites Produced by Macrophomia phaseolus and Analysis of Its Chemical Compounds Using GC-MS Al-Rubaye Abeer Fauzi1, Jihadi Mohammed Ghaidaa2, Hameed Imad Hadi3,* 1Department of Biology, College of Science for Women, University of Babylon, Hillah City, Iraq 2Department of Biology, College of Science, University of Al-Qadisiyah, Hillah City, Iraq 3Biomedical Science Department, University of Babylon, College of Nursing, Hillah City, Iraq *Corresponding author: Imad Hadi Hameed Biomedical Science Department, University of Babylon, College of Nursing, Hillah city, Iraq; Phone number: 009647716150716; E-mail: imad_dna@yahoo.com
Online published on 3 April, 2018. Abstract Twenty one bioactive compounds were identified in the methanolic extract of Macrophomia phaseolus. GC-MS analysis of Macrophomia phaseolus revealed the existence of the Benzonitrile, m-phenethyl, Carbamic acid, N, N-dimethyl-, 3, 4-dimethylphenyl ester, 3-Cyano-6-oxopyrazolo[3, 4-d]pyrimidin-4-thione, 4H-Benz[b]1, 4-oxazin-2(3H)-one, 7-nitro-3-(2-oxo-2-phenylethy, 1-Benzenesulfonyl-1H-pyrrole, Pentyl glycolate, Ethyl fluoroformate, Cyclopropyl-3, 4-epoxyhex-5-en, Benzimidazole, 7-methyl-, 1, 1-Difluoro-cis-2, 3-dimethyl-cyclopropane, Pyrazolo[1, 5-a]pyridine, 3-methyl-2-phenyl-, N, N-Dimethyl-3-methoxy-4methylphenethylamine, 1, 1’-Bicyclohexyl, 4-methoxy-4’-propyl-, 1-benzylindole, and Benzenemethanol, 2-chloro-α-[[(1-methylethyl)amino) methyl. Datura stramonium (Alkaloids) was very highly active 6.61±0.26 mm. The results of anti-fungal and anti-bacterial activity produced by Macrophomia phaseolus showed that the volatile compounds were highly effective to suppress the growth of Aspergillus flavus 6.009±0.23mm and Proteus mirabilis 6.38±0.22mm. Top Keywords Antifungal, Antibacterial, Macrophomia phaseolus, GC-MS, Secondary metabolites. Top |