Screening of Metabolites Products of Fusarium oxysporum and Determination of Its Antibacterial and Antifungal Activity Using Medicinal Plants Extract Al-Rubaye Abeer Fauzi1, Hameed Imad Hadi2,*, Kamal Sabreen A1 1Department of Biology, College of Science for Women, University of Babylon, Hillah city, Iraq 2Biomedical Science Department, University of Babylon, College of Nursing, Hillah city, Iraq *Corresponding author: Imad Hadi Hameed Biomedical Science Department, University of Babylon, College of Nursing, Hillah city, Iraq; Phone number: 009647716150716; E-mail: imad_dna@yahoo.com
Online published on 3 April, 2018. Abstract The aims of this study were screening of the secondary metabolite products and evaluation antimicrobial activity. Bioactives are chemical compounds often referred to as secondary metabolites. Twenty one bioactive compounds were identified in the methanolic extract of Fusarium oxysporum. The identification of bioactive chemical compounds is based on the peak area, retention time molecular weight and molecular formula. Melissa officinalis was very highly active 6.470±0.25 mm. The results of anti-fungal and anti-bacterial activity produced by Fusarium oxysporum showed that the volatile compounds were highly effective to suppress the growth of Aspergillus fumigatus (5.893±0.20) and Streptococcus pyogenes (6.001±0.19). Based on the significance of employing bioactive compounds in pharmacy to produce drugs for the treatment of many diseases, the purification of compounds produced by Fusarium oxysporum can be useful. Top Keywords Antifungal, Antibacterial, Fusarium oxysporum, GC-MS, Secondary metabolites. Top |