A Study of Perception and Motives Towards Participation in Clinical Research in India Marwah Amit1, Ahmed Neyaz2, Nidhi2, Ranjan Rajesh3,*, Singh Mitasha4, Pal Ranabir5 1Adjunct Professor, Jamia Hamdrad, New Delhi-110062 2Department of Centre for Translational and Clinical Research, Faculty of Science and Dept. of Pharmacology, Faculty of Pharmacy, Jamia Hamdrad, New Delhi-110062 3Associate Professor, ESIC Medical College and Hospital, Faridabad, Haryana-121001 4Assistant Professor, ESIC Medical College and Hospital, Faridabad, Haryana-121001 5Professor and Head, Department of Community Medicine, ESIC Medical College and Hospital, Faridabad, Haryana-121001 *Corresponding Author: Dr. Rajesh Ranjan Associate Professor, Department of Community Medicine, ESIC Medical College and Hospital, Faridabad, Haryana-121001 Ph: 9212736852 Email: rajesh.dr.ranjan@gmail.com
Online published on 5 May, 2018. Abstract Background Clinical trials involving healthy volunteer studies can be considered to be a double edged sword. Increased participation from developing countries raises various ethical queries. Objective To explore the perception and motivating factors toward participation in bioavailability and bioequivalence (BA/BE) studies. Methodology Healthy volunteers (200) within the age group 18–45 years who signed the informed consent and underwent screening procedure with the intention to participate in BA/BE studies at Clinical Pharmacology unit, Majeedia Hospital, Jamia Hamdard, New Delhi were included in the study. Results The randomly selected 200 healthy volunteers reported that health benefits were the major reason for participating in the studies (57.5%). The perception about the outcome of these clinical trials was positive among all the volunteers, with 47.5 percent believing that safe medicines will be produced through these experiments. Majority of the participants (76%) had earlier participated in healthy volunteer studies. Conclusion Increasing proportion of professional volunteers needs a check. Due consideration needed to consider the motivating factors for recruiting participants in future trials. Top Keywords Motives and perception, BA/BE studies, trials, India, healthy volunteer. Top |