Immunological status of mumps in infertile individuals in comparison to children Bado Dandan Abdul Wahed1, Majeed Hala Mohamed2,*, Alsamarai Abdulghani Mohamed3 1Department of Pathological Analysis, Tikrit University College of Science, Tikrit, Iraq; 2College of Veterinary Medicine, University of Tikrit, Tikrit, Iraq; 3Asthma, Allergy Centre, Tikrit Teaching Hospital, Tikrit, Iraq *Corresponding Author: Hala M. Majeed Assist. Prof., College of Veterinary Medicine, University of Tikrit, Tikrit, Iraq Email: m.hala17@yahoo.com
Online published on 25 September, 2018. Abstract Mumps is spread easily through the airborne spray from the upper respiratory tract..A Cross-sectional prospective study conducted in Tikrit Teaching Hospital and Primary Health Care Centers. The study population included adults and children from both gender. the adults population group are to be recruited from university students, while the children are to be recruited from 6th primary, 1st, 2nd and 3rd secondary schools. the sample size is 100 subjects in each adults and children groups [50 subject male and 50 female]. Thus a minimum of 200 subjects to be included in the study. Data on vaccination was taken directly from the each individual or vaccination cards if available. ELISA was used for determination of IgG for mumps diseases in central research Laboratory and Tikrit Laboratory's. the tests were performed according to manufacturer instructions. Optical density mean value was with predictive value for mumps antibodies concentration. The mumps mean serum value was lower in adult subjects as compared to child group. This finding indicated that immune response to mumps decreased with time and contribute to resurgence of mumps in community. The frequency of mumps non immune status was higher in adults as compared to child. Additionally, mumps immune response with high titer was significantly lower in adults than in children. The high titer rate was 2 times more in children than in adults. These figures indicated that IgG mumps antibody concentration confirmed the possibility of immune reduction with age and explain the outbreak of the disease in vaccinated subjects. The mean serum mumps IgG concentration was higher in male as compared to female, but not significant. In children, the mean serum mumps IgG was significantly higher in child male as compared to child female. Thus, this study finding do confirm that immune response to mumps vaccination was affected by gender and more intensive in male. The mean mumps serum IgG values were significantly higher in child male as compared to adult male. Top Keywords Immunological, status, mumps, infertile, individuals, comparison children. Top |