Indian Journal of Scientific Research
Year : 2018, Volume : 9, Issue : 1
First page : ( 55) Last page : ( 63)
Print ISSN : 0976-2876. Online ISSN : 2250-0138.
Article DOI : 10.5958/2250-0138.2018.00011.1

Rational of employing carbon nanotuebs in anticancer therapeutics

Dr. Lal Samridhi

University of Central Lancashira, Preston, U.K.

Online published on 6 September, 2019.

Abstract

Research on carbon nanotubes based anticancer drug delivery systems are gaining popularity because of various advantages over classical drug delivery systems including tumour targeting and improvement in the stability of drug molecules in the biological milieu. Nanotubes based anticancer formulations have shown a significant effect on cancer cell lines over various drugs currently available in the market. Due to their chemical structure and drug loading properties, they could be used as drug loaded cargo for delivery of anticancer agents. Moreover, their tumour targeting property is also been reported in hypoxic tumour cell lines where classical agents have failed to kill the cancer cells in a significant manner. This review focuses on various problems in anticancer drug delivery, ways and the rationale of tumour targeting by drugs, and structure of carbon nanotubes along with the methods of attachment of drug molecules on the nanotubes including their advantages over classical drug delivery in cancers.

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Keywords

Anticancer drug delivery, single walled carbon nanotubes, cancer cells.

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