Journal of Camel Practice and Research
Year : 2019, Volume : 26, Issue : 3
First page : ( 251) Last page : ( 254)
Print ISSN : 0971-6777. Online ISSN : 2277-8934.
Article DOI : 10.5958/2277-8934.2019.00039.0

Antibacterial functions of neutrophil and monocyte in newborn dromedary camel calves

Hussen Jamal*

Department of Microbiology and Parasitology, College of Veterinary Medicine, King Faisal University, Al Ahsa, Saudi Arabia

*email: jhussen@kfu.edu.sa

Online published on 30 January, 2020.

Abstract

Newborn camel calves show recurrent infections with higher mortality rates in comparison to adult camels. It is unknown, whether these infections are related to reduced antimicrobial function of innate immune cells. The objective of the current study was to evaluate the impact of age on the phagocytosis function of neutrophils and monocytes in dromedary camel. Phagocytosis of Staphylococcus aureus by blood neutrophils and monocytes collected from newborn camel calves and adult camels was analysed by flow cytometry. In comparison to the cells collected from adult camels, newborn calf neutrophils and monocytes showed lower percentages of phagocytosis positive cells. The analysis of phagocytosis capacity (number of bacteria ingested by each cell) as measured by the mean fluorescence intensity (MIF) of phagocytosis positive cells revealed reduced phagocytosis capacity of newborn calf monocytes in comparison to adult monocytes. Together, these results show impaired antimicrobial functions of neutrophils and monocytes from newborn camel calves.

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Keywords

Flow cytometry, monocyte, neutrophil, newborn camel, phagocytosis.

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