Year : 2023, Volume : 30, Issue : 3
First page : ( 251) Last page : ( 256)
Print ISSN : 0971-6777. Online ISSN : 2277-8934. Published online : 2023 December 25.
Article DOI : 10.5958/2277-8934.2023.00032.2

Camel Cloning: Achievements and Consequences

Niasari-Naslaji Amir

Department of Theriogenology, Faculty of Veterinary Medicine, University of Tehran

SEND REPRINT REQUEST TO AMIR NIASARI-NASLAJI email: niasari@ut.ac.ir

Online Published on 25 December, 2023.

Abstract

The natural process in producing an offspring is through in vivo fertilisation of an oocyte by sperm. Animal cloning via somatic cell nuclear transfer (SCNT) provided the possibility of producing live offspring independent of gametes’ interaction. The procedure involves the reconstruction of an enucleated oocyte with a somatic cell followed by nuclear reprogramming of the differentiated diploid nucleus to an undifferentiated totipotent embryonic state. This allows the reconstructed embryo to grow and produce offspring nearly similar to the original animal that dedicated the somatic cell. SCNT is a very expensive technique and due to the numerous unknown signals involved in nuclear reprogramming and epigenetics, it has extremely low efficiency and low survival rates of offspring. Extensive use of this technique is associated with the reduction in genetic diversity. Nevertheless, it provides an opportunity to preserve an endangered breed of camel or to resurrect the deceased elite camel. This review concentrates on the efficiency of SCNT in dromedary camels and the possibility of using this technique in routine practice.

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Keywords

Animal cloning, Camel, Reproductive technologies.

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