Effect of Different Doses of Volatile Oil Extract of Rosemary in Suckling Rats on Some Physiological Parameters and Pups Basheer A.J.1, Al-Hayyali F.Q.M.1,*, Al-Kassim N.A.H2 1Department of Biology, College of Science, University of Mosul, Mosul, Iraq 2College of Veterinary Medicine, University of Mosul, Mosul, Iraq *Corresponding Author: F.Q.M. Al-Hayyali, Department of Biology, College of Science, University of Mosul, Mosul, Iraq, Email: marwanmerkhan@uomosul.edu.iq
Online Published on 06 January, 2024. Abstract Background The current study was carried out in the animal house-College of the Veterinary Medicine/University of Mosul-Iraq. The study aimed to evaluate the effects of volatile oil extract of rosemary on some physiological and reproductive parameters of suckling female rats and their pups. Methods 24 suckling female rats were used and have been distributed randomly to four groups 6 suckling female rats for each group. The first group was considered a control group that was administered only with corn oil orally while the other groups were treated orally with volatile oil extract of rosemary 250,500, 1000 mg/kg body weight for 21 days (time of suckling). Result Results revealed that the treatment of suckling female rats with volatile oil extract of rosemary caused a significant P<0.05 decrease in body weight of suckling female and its pups in 7,14,21 days of suckling time and an increase significantly P<0.05 the mortality of suckling female and its pups, as well as increase the growth factor of pups(days) significantly which include (open of ears, obtained of hair, obtain of teeth and opened of the eyes), compared with the control group. Doses of volatile oils extract of rosemary (250, 500, 1000 mg/kg b.w.) caused a significant P<0.05 increase of testicular descent and primary preputial separation of male suckling pups (days) and a decrease significantly P<0.05 Ano-gential distance (AGD)/mm, as well as increased vaginal opening significantly P<0.05 of female suckling pups compared with the control group. There was a significant decrease P<0.05 in each of estrogen, prolactin, FSH and LH in all doses of rosemary oil used in the study, while there was no significant difference in progesterone copared to the control group in suckling females. Top Keywords Albino rats, Physiological changes, Rosemary oil, Volitale oil. Top |