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Journal of Orofacial & Health Sciences
Year : 2018, Volume : 9, Issue : 2
First page : ( 76) Last page : ( 78)
Print ISSN : 0976-5360. Online ISSN : 2229-3264.
Article DOI : 10.5958/2229-3264.2018.00015.1

Periodontal vaccines: Need of an hour

Kapoor Shalini1,*, Arora Pallak2, Sheokand Vidushi3, Saxena Neha4, Wazir Sartaj Singh5

1Reader, Department of Periodontics and Oral Implantology, SGT University, Gurugram, Haryana

2Reader, Department of Oral Medicine & Radiology, DJ College of Dental Sciences, Modinagar, Uttar Pradesh, India

3Senior Lecturer, Department of Periodontics and Oral Implantology, SGT University, Gurugram, Haryana

4Senior Lecturer, Department of Periodontics and Oral Implantology, SGT University, Gurugram, Haryana

5Associate Professor, Department of Oral Medicine & Radiology, MB Kedia Dental College, Birgunj, Nepal

*Address for correspondence: Shalini Kapoor Email Id: dr_shalinibasur@yahoo.co.in

Online published on 28 January, 2019.

Abstract

Periodontal diseases are immune inflammatory responses induced by microorganisms in dental plaque which contributes to tissue destruction, bone loss and eventually tooth loss. Moderate-to-severe periodontitis affects more than 50 per cent of population over the age of 65. It is also associated with diabetes, heart disease, rheumatoid arthritis, dementia and certain cancer. Current treatment modalities have resulted only in arresting the disease progression but have no solution for curing the disease or to prevent the recurrence. Hence, there is a need for more sophisticated therapeutic modalities which may include vaccines targeting putative periodontal pathogens. Periodontal vaccines could emerge as an adjunct to mechanical therapy in future.

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Keywords

Periodontal vaccine, Pathogens, Treatment modalities.

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