Carbamazepine induced drug hypersensitivity-A case report Bhagat Vasuda1,*, Arora Pallak2, Ranjan Vikash2, Rastogi Trisha3 1Post Graduate Student, Department of Oral Medicine & Radiology, Divya Jyoti College of Dental Sciences and Research, Modinagar, Uttar Pradesh, India 2Reader, Department of Oral Medicine & Radiology, Divya Jyoti College of Dental Sciences and Research, Modinagar, Uttar Pradesh, India 3Divya Jyoti College of Dental Sciences and Research, Modinagar, Uttar Pradesh, India *Address for correspondence: Vasuda Bhagat Email Id: vasudhabhagat1991@gmail.com
Online published on 28 January, 2019. Abstract Drug allergies are unpredictable and immunologic adverse effects, usually with immunoglobulin E-mediated immediate hypersensitivity or T-cell-mediated delayed hypersensitivity. The drug-induced hypersensitivity syndrome has high morbidity and rare mortality. These reactions are typically unpredictable. They can be fatal, may require hospitalisation, and may necessitate changes in subsequent therapy. Carbamazepine is the main drug used to treat seizure disorder, bipolar disorder, trigeminal neuralgia, and chronic pain and is one of the most common causes of drug hypersensitivity reactions. The reported frequency of serious carbamazepine hypersensitivity reaction is between 1/1, 000 and 1/10, 000 new exposures to the drug. Here, we report a case of a 58-year-old male patient, who developed fixed drug eruptions after the ingestion of first dose of carbamazepine. Top Keywords Carbamazepine, Drug hypersensitivity reaction, Trigeminal neuralgia. Top |