An overview of the malaria parasite biology, host-parasite interactions, and malaria control strategies Basagoudanavar Suresh H.1,*, SubbaRao V. Madhunapantula2,*, Gowda D. Channe** Department of Biochemistry and Molecular Biology, Pennsylvania State University College of Medicine, Hershey, PA 17033, USA **Corresponding author: Tel: 717–531-0992; Fax: 717–531-7072; E-mail: gowda@psu.edu
1Present address: Department of Microbiology and Immunology, Pennsylvania State University College of Medicine, Hershey, PA 17033, USA
2Present address: Department of Pharmacology, Pennsylvania State University College of Medicine, Hershey, PA 17033, USA
*SHB and SVM contributed equally.
Abstract Malaria, caused by the protozoan parasites of the genus Plasmodium, remains one of the most devastating global health problems. In the past two decades, there has been tremendous expansion of knowledge on malaria. Investigations into molecular and immunobiology of the parasite are providing insights into the mechanisms that underlie the pathogenesis. In this article, the available information on the Plasmodium biology, host–parasite interactions and malaria control strategies are summarised. Top Keywords Malaria, Plasmodium spp., Host-parasite interactions, Immune responses, Disease pathogenesis, Vaccine strategies. Top |