Prevalence of Congenital Hypothyroidism; in Rural Area of District Gautam Budha Nagar (U.P.) Sharma Chandra Prakash1, Dubey Widhi2, Nagtilak Suryakant3,* 1Research Scholar, JECRC University, Ramchandrapura, Sitapura, Jaipur (Rajasthan) 2Prof. & Director, School of Science, JECRC University, Ramchandrapura, Sitapura, Jaipur (Rajasthan) 3Prof. & Head, Dept. of Biochemistry, Sridev Suman Subharti Medical College, Dehradun (Uttrakhand) *Corresponding Author: Dr. Suryakant Nagtilak, Email: nagtilak@yahoo.com
Online published on 8 August, 2019. Abstract Introduction Congenital hypothyroidism is a condition that affects the newborns and results from a partial or complete loss of thyroid function. Congenital hypothyroidism occurs when the thyroid gland fails to develop the thyroid hormone or do not function properly. In 80 to 85 percent of cases, the thyroid gland is absent, abnormally located, or severely reduced in size. In the remaining cases, a normal-sized or enlarged thyroid gland is present, but production of thyroid hormones is decreased or absent. If untreated, congenital hypothyroidism can lead to intellectual disability and abnormal growth. Iodine is an essential dietary element which is required for the synthesis of the thyroid hormones, thyroxine (T4) and tri-iodothyronine (T3). In endemic goiter areas, congenital hypothyroidism may occur due to iodine deficiency. Aim To screen the Rural area's neonates for Congenital Hypothyroidism. Results The prevalence of CH is 4/161 live birth observed in the rural area of Gautam Buddha Nagar District and it also observed that the mean level of TSH was higher in female compared to male neonates. Conclusion Despite the overwhelming evidence of a high prevalence of CH in India, this imminently treatable cause for developmental delay and mental retardation continues to await a credible universal screening programme. To get the actual picture of CH in the study area is to need to screen more neonates, which helps to make the more precise evaluation of CH. Top Keywords Thyroid stimulating hormone (TSH), Thyroxine, and congenital hypothyroidism (CH). Top |