Phytochemical analysis of Baliospermum montanum leaves and evaluation of In vitro anticoagulant, antioxidant and anticancer properties Shoba Esther R.*, Sivagamasundari U., Devi Vaishnavi V., Josely Ashley Elsa, Afreen Johar I., Valiyapurayil Kavya Manoj Department of Life Sciences, Kristu Jayanti College, Bangalore-560077, Karnataka, India *Corresponding author e-mail: esther@kristujayanti.com
Online published on 29 June, 2023. Abstract Plants’ bioactive components, or phytochemicals, have long been known to have therapeutic properties. These therapeutic herbs are currently in high demand due to their natural characteristics. Baliospermum montanum is an herbaceous, thick undershrub with blooms of the Euphorbiaceae family. Commonly this plant is known as sultan seed, wild croton and wild castor. This plant's roots treat jaundice, leukoderma, skin disorders, and wounds. The plant leaves have been useful in treating respiratory disorders such as asthma and bronchitis, as well as stomach tumours. Seeds of the plant have laxative properties and can help with gastrointestinal issues. In the present work, the phytochemical content of ethanol extract of B. montanum leaves has been studied and assayed for its antioxidant, anticoagulant and cytotoxic properties. On human alveolar lung adenocarcinoma cell line (NCI-H460), the extract showed IC50 concentration at 70.2 μg/ml after 24 hrs against the IMR-90 cells, which showed the IC50 concentration of 137.24 μg/ml. This result showed the plant to be a potential phytochemicals to treat lung cancer patients. Further exploration on the identification of phytochemicals with different solvents for the extract and characterisation of the bioactive compounds will be more promising in pharmaceutical uses. Top Keywords Phytochemicals, Anticoagulant, Cytotoxicity, Antioxidants. Top |