Validation of tribal claims for formulation of future drugs through evaluation of ethno-pharmacological values of Ludwigia adscendens Devi Rajkumari Supriya1, Satapathy Kunja Bihari1, Kumar Sanjeet2,* 1School of Applied Sciences, Centurion University of Technology and Management, Bhubaneswar-752050, Odisha, India 2Biodiversity and Conservation Laboratory, Ambika Prasad Research Foundation, Cuttack-753014, Odisha, India *Corresponding author e-mail: sanjeet.biotech@gmail.com
Online published on 26 December, 2023. Abstract Ludwigia adscendens (L.) H. Hara belongs to family Onagraceae, a wetland flora abundantly available in and around Loktak Lake, Manipur, India. The local community of the lake use this plant for various purposes. It has been used for many medicinal purposes against toothache, stomach problems like diarrhoea, food poisoning or as a natural antiseptic. Keeping this in view, an attempt has been made to evaluate ethnopharmacological values of this plant species. A survey was made during 2019 and collected the ethnomedicinal information and plant parts for the experimental works. Plant extracts were prepared using maceration and Soxhlet method for phytochemical analysis and antimicrobial activity, respectively. The phytochemical analysis and biological evaluation of the plant parts showed the rich content of phenolic compounds, flavonoids, and tannins. Antimicrobial activity and MIC for this plant extract (acetone, methanol, and aqueous extract) was checked on different selected pathogens i.e., Staphylococcus mutans and Shigella flexneri. Result of this study showed inhibition of microbial growth for (AWD) in 100 mg/ml concentration and MIC of 50 mg/ml concentration. This plant could be screened for further analysis of identifying the active secondary metabolites responsible for its medicinal values and future drug development for antimicrobial resistance. Top Keywords Water primrose, Loktak lake, Ethnopharmacology, Formulation, Future drugs. Top |