Nuance of nucleated rbcs (normoblastemia) in peripheral blood film Akhtar S1,*, Mahure S2 1Assistant Professor, Department of Pathology, NKP SIMS & RC, Digdoh Hills, Hingna Road, Nagpur-440019 2Professor, Department of Pathology, NKP SIMS & RC, Digdoh Hills, Hingna Road, Nagpur-440019 * akhtar_lmh@rediffmail.com
Online published on 9 November, 2015. Abstract Nucleated RBCs (NRBCs) are immature RBCs normally they are not seen in the peripheral blood after the neonatal period. Their presence in peripheral blood of children and adults signifies bone marrow damage or stress and potentially serious underlying disease. The presence of numerous NRBCs increases the WBC count in automated hematology analyzers. Most analyzers generate suspect flags for identifying abnormal cells, and the samples involved should be reviewed manually. Unfortunately, analyzers may not detect low levels of NRBCs. We recommend correcting the WBC count with even 1 NRBC/100 WBCs and reporting “occasional NRBC seen. ”This alerts clinicians for the significance of unexplained normoblastemia. Top Keywords Nucleated RBCs, Peripheral blood, Normoblastemia. Top |