Antifungal Activity of O, 0-Bisaryl Isopropyl Phosphonates and Relationships Between Chemical Structure and Activity Nidiry Eugene Sebastian J.1, Roy N.K. Division of Agricultural Chemicals, Indian Agricultural Research Institute, New Delhi, 110 012, India 1Present address: Indian Institue of Horticultural Research, Hessaraghatta, Bangalore.
Online published on 15 December, 2011. Abstract The fungitoxicity of twenty O, O-bisaryl isopropyl phosphonates aganst four important fungi, viz. H. oryzae, P. oryzae, A. alternate and F. solani was determined. Of these O, O-bis (2,4,5-trichlorophenyl)-and O, O-bis (pentachlorophenyl) isopropylphosphonates exhibited the highest activity. Structure-activity relationship of the phosphonates showed that changes in hydrophobicity of substituents with the phenyl ring (#x03A3;π) and molar refractivity of substituents at the para-position of the phenyl ring [MR (p)] accounted for the major percentage of variation in the fungicidal activity exhibited by the members of the series against above fungi. Top |