In Vitro Cytotoxic Activity of Leaves of Abutilon indicum Linn. Against Ehrlich Ascites Carcinoma and Dalton's Ascitic Lymphoma Cell Line. Bondre AV1,*, Akare SC1, Mourya P1, Wanjari AD1, Tarte PS1, Paunikar GV1 Department of Pharmacology, Bajiraoji Karanjekar College of Pharmacy, Sakoli, Dist. Bhandara. (M.S) 441802 1Department of Pharmacology, Guru Ramdas Khalsa Institute of Science and Technology, Jabalpur. (M.P) India *Corresponding Author: Mr. A V Bondre, Lecturer, Department of Pharmacology, Bajiraoji Karanjekar College of Pharmacy, Sakoli, Dist. Bhandara. (M.S) 441802 India, E-mail: amolbondre1984@rediffmail.com
Online published on 22 March, 2013. Abstract Alcohol and aqueous extracts from the leaves of Abutilon indicum Linn. Were investigating for their cytotoxic activity against EAC and DLA cell line. Various concentrations (10–200μg/ml) of each extract were treated in trypan blue method. Which involved determination of number of dead cells/total 100 cells counted gives the percentage of cytotoxicity was calculated. Both the extract exhibited significant cytotoxic activity at higher concentration of 200μg/ml. Distilled water used as a control. Top Keywords Abutilon indicum, cytotoxic activity, Ehrlich Ascites Carcinoma (EAC), Dalton's Ascitic Lymphoma (DLA). Top |