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Research Journal of Pharmacology and Pharmacodynamics
Year : 2009, Volume : 1, Issue : 1
First page : ( 18) Last page : ( 20)
Print ISSN : 0975-4407.

Anti-ovulatory and Abortifacient Potential of the Ethanolic Extract of Henna Roots in Rats

Rani S*, Manavalan R, Kilimozhi D

Department of Pharmacy, Annamalai University, Annamalai Nagar-608002, Tamil Nadu. India

*Corresponding Author: S. Rani, Lecturer, Department of Pharmacy, Annamalai University, Annamalai Nagar -608002, Tamil Nadu. India. E -Mail: ranishan2006@rediffmail.com. Phone: +91-9976997018.

Online published on 20 March, 2013.

Abstract

The rise in population in the developing world is over whelming and this intensifies the need for effective birth control measures. The synthetic agents available today for fertility control produce severe side effects. Such as hormonal imbalance, hypertension, increased risk of cancer and weight gain. Thus there is a need to replace these agents by safe and effective agents such as plants based contraceptive agents.

Therefore, the present study was under taken to explore the abotifacient and antiovulatory activity of ethanol extract of henna roots. Thus, the successive ethanolic extract showed promising strong abotifacient and antiovulatory activity was observed at dose level of 400mg/kg body weight. Histological studies were carried out to confirm this effect.

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Keywords

Abortifacient, ovulation, contraception.

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